91¹ú²úÊÓÆµ

Jeffrey M Rosen

Rosen

Jeffrey M Rosen, Ph.D.

Distinguished Service Professor

(713) 798-6210

Positions

Distinguished Service Professor
Mol & Cell Biology-Rosen
91¹ú²úÊÓÆµ
Houston, TX, US
Leader, Breast Cancer Program
Dan L Duncan Comprehensive Cancer Center
91¹ú²úÊÓÆµ
Houston, Texas, United States
Professor
91¹ú²úÊÓÆµ
Charles C. Bell Professor
Molecular and Cellular Biology

Addresses

Department of Molecular and Cellular Biology (Office)
91¹ú²úÊÓÆµ
One Baylor Plaza N610
Houston, TX, 77030
United States
Phone: (832) 215-9503
jrosen@bcm.edu

Education

BA from Williams College
01/1966 - Williamstown, Massachusetts, United States
PhD from State University of New York at Buffalo
01/1970 - Buffalo, New York, United States
Post-Doctoral Fellowship at Vanderbilt University School of Medicine
01/1972 - Nashville, Tennessee, United States

Honors & Awards

Marc Dresden Excellence in Graduate Education Award, 1996
Endocrine Society Edwin B. Astwood Lecture Award 2000
Barbara & Corbin J. Robertson, Jr. Presidential Award for Excellence in Education, 91¹ú²úÊÓÆµ, 2002
Michael E. DeBakey, M.D., Excellence in Research Award, 2004.
Susan G. Komen for the Cure® Brinker Basic Science Award, 2010
AAAS Fellow, 2016
AACR Distinguished Lectureship in Breast Cancer Research, 2017
AACR/SABCS William A McGuire Memorial Lecture Award
AACR/SABCS (12/2022)

Professional Interests

  • Developmental and hormonal regulation of mammary gland gene expression and breast cancer

Professional Statement

Our laboratory has developed a series of extensively characterized and "credentialed" syngeneic models of triple negative breast cancer that are being used in preclinical studies to determine both tumor intrinsic and extrinsic effects on the tumor microenvironment of both targeted therapies using small molecular inhibitors as well as gapmer antisense oligonucleotides. These studies are focused on combinatorial treatment strategies with standard-of care chemotherapy and immunotherapy of both primary tumors and established metastases with the long-term goal of translating these studies into the clinic.

Websites

Selected Publications

  • Kim, IS, Welte, T, Gao, Y, Toneff, MJ, Wang, H, Janghorban, M, Zhao, N, Goldstein, A, Sheng, K, Niu, Y, Liu, J, Lo, H-C, Bado, I, Nguyen, T, et al. and Rosen, JM, Zhang, X H-F.. " " Nature Cell Biol. 2019 ; 21 : 1113-1126.
    Pubmed PMID: .
  • Nguyen, TM, Kabotyanski, EB, Dou, Y, Reineke, LC, Zhang, P, Zhang, X, Malovannaya, A, Jung, SY, Mo, Q, Roarty, K, Chen, Y, Zhang, B, Neilson, JR, Lloyd, RE, Perou, CM, Ellis, MJ and Rosen, JM.. " " Cancer Res. 2018 ; 78 : 4229-4240.
    Pubmed PMID: .
  • Sreekumar A, Toneff MJ, Toh E, Roarty K, Creighton CJ, Belka GK, Lee DK, Xu J, Chodosh LA, Richards JS, Rosen JM. " " Dev Cell. 2017 ; 43 : 436-448.
    Pubmed PMID: .
  • Welte, T., Kim, IS, Tian, L, Gao, X, Wang, H., Li, J. Holdman, X.B., Herschkowitz, J.I., Pond, A., Xie, G., Kurley, S, Nguyen, T, et al and Westbrook, T, Rosen, JM. and Zhang, XH. " " Nature Cell Biol. 2016 ; 18 : 632-644.
    Pubmed PMID: .

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