91¹ú²úÊÓƵ

Email

mzhou@bcm.edu

Positions

Professor

Biochemistry and Molecular Biology
91¹ú²úÊÓƵ
Houston, Texas, United States

Ruth McLean Bowman Bowers Professorship in Biochemistry

Biochemistry and Molecular Biology
91¹ú²úÊÓƵ
Houston, Texas, United States

Member

Dan L Duncan Comprehensive Cancer Center
91¹ú²úÊÓƵ
Houston, Texas, United States

Addresses

91¹ú²úÊÓƵ (Office)

BCM-Smith Medical Research Bldg
Room: BCMS-313
Houston, TX, 77030
United States

Education

Postdoctoral Fellowship at The Rockefeller University

08/2004 - NY, New York, United States

Mechanisms of the N-type inactivation gating and of ion permeation in potassium ion channels by X-ray crystallography and electrophysiology

PhD from State University Of New York At Buffalo

07/1999 - Buffalo, New York, United States

Mechanism of ligand recognition and channel gating in acetylcholine receptor channels by single-channel recordings and kinetic analyses

Honors & Awards

Pew Scholar in Biomedical Science

(01/2006)

Alfred P. Sloan Fellow

(01/2006)

Basil O’Connor Starter Scholar Award

(01/2006)

Irma Hirschl Award

(01/2008)

Professional Interests

• Membrane Transport Proteins and Membrane Embedded Enzymes
• Neuroscience
• Metabolism
• Enzymology
• Structural Biology
• Biomembranes
• Cancer Biology
• Chemical Biology
• Drug Discovery and Medicinal Chemistry

Professional Statement

Websites

Selected Publications

• Wang L, Qian H, Nian Y, Han Y, Ren Z, Zhang H, Hu L, Prasad BVV, Laganowsky A, Yan N, & Zhou M. " " Nature. 2020 May 13; 581 (7808) : 329-332.
  Pubmed PMID: .
• Zhang H, Pan Y, Hu L, Hudson MA, Hofstetter KS, Xu Z, Rong M, Wang Z, Prasad BVV, Lockless SW, Chiu W, Zhou M. " " Nature Communications. 2020 Jan 28; 11 (1) : 547.
  Pubmed PMID: .
• Ren Z, Lee J, Moosa MM, Nian Y, Hu L, Xu Z, McCoy JG, Ferreon ACM, Im W, Zhou M. " " Proc Natl Acad Sci U S A.. 2018 May 21; 115 (23) : 5962-5967.
  Pubmed PMID: .
• Bai Y, McCoy JG, Levin EJ, Sobrado P, Rajashankar KR, Fox BG, Zhou M. " " Nature. 2015 Aug 13; 524 : 252-256.
  Pubmed PMID: .
• Huang H, Levin EJ, Liu S, Bai Y, Lockless SW, Zhou M. " " PloS Biol. 2014 Jul 22; 12 (7) : e1001911.
  Pubmed PMID: .
• Zhou X, Levin EJ, Pan Y, McCoy JG, Sharma R, Kloss B, Bruni R, Quick M, Zhou M,. " " Nature. 2014 Jan 23; 505 (7484) : 569-73.
  Pubmed PMID: .
• Cao Y, Pan Y, Huang H, Jin X, Levin EJ, Kloss B, Zhou M.. " " Nature. 2013 Apr 18; 496 (7445) : 317-22.
  Pubmed PMID: .
• Pan Y, Levin EJ, Quick M, Zhou M.. " " ACS Chem. Biol.. 2012 Oct 19; 7 (10) : 1641-6.
  Pubmed PMID: .
• Levin EJ, Cao Y, Enkavi G, Quick M, Pan Y, Tajkhorshid E, Zhou M.. " " Proc Natl Acad Sci USA. 2012 Jul 10; 109 (28) : 11194-11199.
  Pubmed PMID: .
• Cao Y, Jin X, Levin EJ, Huang H, Zong Y, Quick M, Weng J, Pan Y, Love J, Punta M, Rost B, Hendrickson WA, Javitch JA, Rajashankar KR, Zhou M.. " " Nature. 2011 May 5; 473 (7345) : 50-4.
  Pubmed PMID: .
• Pan Y, Weng J, Levin EJ, Zhou M.. " " Proc Natl Acad Sci. 2011 Apr 5; 108 (14) : 5885-90.
  Pubmed PMID: .
• Cao Y, Jin X, Huang H, Derebe MG, Levin EJ, Kabaleeswaran V, Pan Y, Punta M, Love J, Weng J, Quick M, Ye S, Kloss B, Bruni R, Martinez-Hackert E, Hendrickson WA, Rost B, Javitch JA, Rajashankar KR, Jiang Y, Zhou M.. " " Nature. 2011 Mar 17; 471 (7338) : 336-40.
  Pubmed PMID: .
• Levin EJ, Quick M, Zhou M.. " " Nature. 2009 Dec 10; 462 (7274) : 757-61.
  Pubmed PMID: .
• Pan Y, Weng J, Cao Y, Bhosle RC, Zhou M.. " " J. Biol. Chem.. 2008 Mar 28; 283 (13) : 8634-42.
  Pubmed PMID: .
• Pan Y, Weng J, Kabaleeswaran V, Li H, Cao Y, Bhosle RC, Zhou M.. " " Nat Chem Biol.. 2008 Nov ; 4 (11) : 708-14.
  Pubmed PMID: .

Show 11 more publications

Memberships

Biophysical Society

member

Protein Society

member