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Will Bauer

Bauer

Will Bauer, MSc

PhD Candidate

Email

will.bauer@bcm.edu

Positions

PhD Candidate
Genetics and Genomics
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Houston, Texas, United States

Education

BSc from Acadia University
04/2020 - Wolfville, Nova Scotia, Canada
Honours in Biology
MSc from McGill University
08/2022 - Montreal, Quebec, Canada
Human Genetics

Professional Interests

  • Inborn Errors of Cobalamin and Folate Metabolism
  • Pathophysiology of Metabolic Inborn Errors of Cobalamin
  • Gene Therapy

Professional Statement

I research the developmental pathophysiology associated with inborn errors of cobalamin (vitamin B12) metabolism, using in vivo genetically engineered mice and in vitro patient-derived fibroblast cultures. Inborn errors of cobalamin metabolism are extensively described clinically, but there is a poor understanding of the cellular origins of associated phenotypes such as retinal degeneration, heart defects, neural tube defects, ataxia, and dementia. By using a developmental biology approach along with advanced techniques in genetics and genomics, we can begin to fill these gaps in knowledge, thereby improving our understanding of cobalamin metabolism and developing more effective therapies.

Websites

Selected Publications

  • Bauer WG, Stewart DT, Céspedes RQ, Arias S, Easy RH. " " Neotrop. Nat.. 2021 Jan ; 5 : 1-8.
  • Cormier M, Ghouili F, Roumand P, Bauer W, Touabia J, Martin LJ. " " Cell Biol Toxi. 2018 ; 34 (1) : 23-38.
  • Bauer WG, Watkins D, Zacharias C, Gilfix BM, Rosenblatt DS. " " Mol. Gen. Met.. 2024 Jan 4; 141 (1)
    Pubmed PMID: .
  • Freeman EJG, Bauer WG, Easy RH, Céspedes RQ, Valverde SA, Stewart DT. " " Malacologia. 2025 ; 67

Projects

PhD Thesis
Genetics and Genomics (01/2023 - present)
Defining the developmental pathophysiology of cblC using in vivo genetically engineered mouse models.
Capstone Project
Clinical Translational Research (01/2024 - 09/2025)
Generating a humanized mouse model for cblC.

Languages

French

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